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| Antigenic Specificity | UAP1L1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | UAP1L1 Polyclonal Antibody. UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a α/β structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males. |
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| Immunogen | n/a |
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| Other Names | UDP-N-acetylhexosamine pyrophosphorylase-like protein 1; 277-; UAP1L1 |
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| Gene, Accession # | Entrez: 91373; Uniprot: Q3KQV9 |
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| Catalog # | PA5-71598 |
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| Price | |
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| Order / More Info | UAP1L1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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