| 产品详情 |
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| Antigenic Specificity | UBA3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | UBA3 Polyclonal Antibody. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have be |
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| Immunogen | n/a |
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| Other Names | NEDD8-activating enzyme E1 catalytic subunit; Ubiquitin-activating enzyme 3; NEDD8-activating enzyme E1C; Ubiquitin-activating enzyme E1C; UBA3 |
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| Gene, Accession # | Entrez: 22200, 9039; Uniprot: Q8C878, Q8TBC4 |
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| Catalog # | PA5-11190 |
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| Price | |
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| Order / More Info | UBA3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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