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| Antigenic Specificity | XBP1 |
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| Clone | 1C4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | XBP1 Monoclonal Antibody (1C4). This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum , the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 . The resulting loss of 26 nt from the |
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| Immunogen | n/a |
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| Other Names | XBP2; TREB5; XBP1 |
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| Gene, Accession # | Entrez: 7494; Uniprot: P17861 |
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| Catalog # | MA5-15626 |
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| Price | |
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| Order / More Info | XBP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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