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| Antigenic Specificity | XBP1 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 5 µg/mL, peptide-ELISA: 1:4000, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | XBP1 Polyclonal Antibody. This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum , the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 . The resulting loss of 26 nt from the splice |
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| Immunogen | n/a |
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| Other Names | XBP1; TREB5; X-box binding protein 1 ; XBP2; OTTHUMP00000028682; X-box-binding protein-1 |
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| Gene, Accession # | Entrez: 7494; Uniprot: P17861 |
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| Catalog # | PA5-18940 |
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| Price | |
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| Order / More Info | XBP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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