| 产品详情 |
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| Antigenic Specificity | XIAP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Immunohistochemistry: 2 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | XIAP Polyclonal Antibody. Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. The X-chromosome linked inhibitor of apoptosis (XIAP) contains 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases-3, -7, and -9. Upregulation of XIAP expression can protect cells from apoptosis induced by low level radiation; conversely, decreased XIAP expression by antisense targeting resulted in increased cell death following low lev |
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| Immunogen | n/a |
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| Other Names | RP1-315G1.5, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3; E3 ubiquitin-protein ligase XIAP; IAP-like protein; X-linked IAP; X-linked inhibitor of apoptosis protein; baculoviral IAP repeat-containing 4; baculoviral IAP repeat-containing protein 4; inhibitor of apoptosis protein 3 |
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| Gene, Accession # | Entrez: 11798, 331; Uniprot: P98170, Q60989 |
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| Catalog # | PA5-20067 |
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| Price | |
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| Order / More Info | XIAP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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