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| Product Name | Recombinant Human UDP-glucuronosyltransferase 1-1 (UGT1A1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 59.1kDa. Full Length of Mature Protein: 26-533aa. N-terminal 6xHis-tagged. Homo sapiens (Human). UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Bilirubin-specific UDPGT isozyme 1; hUG-BR1UDP-glucuronosyltransferase 1-A; UGT-1A; UGT1AUDP-glucuronosyltransferase 1A1 |
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| Gene, Accession, CAS # | UGT1A1, UniProt: P22309 |
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| Catalog # | RPC20247 |
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| Order / More Info | Recombinant Human UDP-glucuronosyltransferase 1-1 (UGT1A1) from BIOMATIK |
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| Product Specific References | n/a |
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