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| Product Name | LTA, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha, TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta, which effectively anchors the TNF-beta to the cell surface. TNF-beta is cytotoxic to a wide range of tumor cells. Source: Recombinant protein corresponding to human LTA expressed in CHO cells. Molecular Weight: ~19kD Biological Activity: The ED50 was Measured in a cytotoxicity assay using mouse L929 cells in the presence of the metabolic inhibitor actinomycin, and was determined to be ≤0.1ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LTA, Recombinant, Human (TNF-Beta, Lymphotoxin-Alpha, LT-Alpha, TNF-Beta, Tumor Necrosis Factor Ligand Superfamily Member 1, TNFSF1, Tumor Necrosis Factor-Beta) |
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| Gene, Accession, CAS # | SwissProt: P01374 |
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| Catalog # | 500217 |
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| Price | |
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| Order / More Info | LTA, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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