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Product Name | Recombinant Human Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 40.1kDa. Partial of Isoform 3: 1-314aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | GC-binding factor 2TAR RNA-interacting protein |
Gene, Accession, CAS # | LRRFIP1, UniProt: Q32MZ4 |
Catalog # | RPC21623 |
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Order / More Info | Recombinant Human Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1), partial from BIOMATIK |
Product Specific References | n/a |
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