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| Product Name | Interferon gamma (IFNG) protein |
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| Description | IFN-gamma, also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The protein shares no significant homology with IFN-beta or the various IFN-alpha family proteins. Mature IFN-gamma exists as noncovalently-linked homodimers. Human IFN-gamma is highly species specific and is biologically active only in human and primate cells. IFN-gamma was originally characterized based on its antiviral activities. The protein also exerts antiproliferative, immunoregulatory and proinflammatory activities and is thus important in host defense mechanisms. IFN-gamma induces the production of cytokines, upregulates the expression of class I and II MHC antigens, Fc receptor and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching and potentiates the secretion of immunoglobulins by B cells. IFN-gamma also augments TH1 cell expansion and may be required for TH1 cell differentiation. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IFNG2|IFN-g|Ifg|IFN-G|IFN-gamma|IFNG|IFG|IFI |
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| Gene, Accession, CAS # | Gene ID: 3458 |
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| Catalog # | ABIN1540288 |
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| Order / More Info | Interferon gamma (IFNG) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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