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| Product Name | Mouse Recombinant DHFR |
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| Description | Dihydrofolate reductase (DHFR) is a member of the reductase family of enzymes that is ubiquitously expressed in all organisms. DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and it is essential for the synthesis of thymidylate, purines and several amino acids. Expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive. MW: 23.8 kDa (207 aa, 1-187 aa + NT His-Tag). Purity ≥95% |
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| Size | 100 µg |
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| Concentration | 1 mg/ml |
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| Applications | RUO |
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| Other Names | Dihydrofolate reductase. |
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| Gene, Accession, CAS # | DHFR, Gene ID: 13361, Accession: P00375 |
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| Catalog # | 6383-100 |
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| Price | |
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| Order / More Info | Mouse Recombinant DHFR from BIOVISION, INC. |
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| Product Specific References | n/a |
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