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| Antigenic Specificity | CD137 Ligand (4-1BB Ligand) |
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| Clone | 4H3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | PE-Cyanine7 conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.06 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD137 Ligand (4-1BB Ligand) Monoclonal Antibody (4H3), PE-Cyanine7, eBioscience™. CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily. CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation. Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes. Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity. CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular |
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| Immunogen | n/a |
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| Other Names | 41BBL, TNFRSF9, 4-1BBL, TNFSF9, CDw137L |
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| Gene, Accession # | Entrez: 8744; Uniprot: P41273 |
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| Catalog # | 25-5906-42 |
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| Order / More Info | CD137 Ligand (4-1BB Ligand) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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