| 产品详情 |
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| Product Name | LG 100754 |
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| Description | Purity >98%. LG 100754 is a ligand of retinoid X receptor (RXR) that modulates the activity of RXR dimers. It acts as an antagonist towards RXR homodimers but as an agonist of heterodimers consisting of RXR and retinoic acid receptor (RAR) or PPARs. LG 100754, at 1 µM, is a weak agonist of RXR-PPARGamma but strongly enhances signaling through the heterodimer in response to PPARGamma ligands, including rosiglitazone and 15-deoxy-Delta12,14 -prostaglandin J2 . Through this action, LG 100754 decreases glucose levels and relieves insulin resistance in mice. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-2-naphthalenyl)-2E,4E,6Z-octatrienoic acid, CD3159, LGD 100754, UVI2112 |
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| Gene, Accession, CAS # | CAS: 180713-37-5 |
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| Catalog # | LS-H8462 |
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| Order / More Info | LG 100754 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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