| 产品详情 |
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| Antigenic Specificity | EBP50 |
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| Clone | EBP-10 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EBP50 Monoclonal Antibody (EBP-10). NHERF1 (Na+/H+ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50) is an adaptor protein, which associates with beta-catenin and is required for its localization at the cell-cell junctions, interacts with various G protein-coupled receptors and regulates their traffic, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport. NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains and is able to form head-to-tail intramolecular conformation to regulate |
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| Immunogen | n/a |
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| Other Names | EBP50 |
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| Gene, Accession # | Entrez: 9368; Uniprot: O14745 |
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| Catalog # | MA1-19291 |
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| Price | |
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| Order / More Info | EBP50 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21672215 |
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