| 产品详情 |
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| Product Name | Thio-TEPA |
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| Description | An alkylating agent with anticancer activity (IC50 = 1.5 µM against P388 murine leukemia cells); alkylates DNA and inhibits thymidine incorporation (IC50 = 2 µM) inducing irreversible DNA damage; crosslinks guanine nucleotides and induces cell cycle arrest via the formation of interstrand cross-links in L1210 and MCF-7 cancer cells in vitro; reduces the number of pulmonary metastases in mice following subcutaneous injection of melanoma cells; decreases the number of postoperative lung metastases when administered at a dose of 10 mg/kg after surgical removal of an S-91 melanoma tumor established via intramuscular injection in mice |
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| Size | 250 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NCI C01649|NSC 6396|Triethylenethiophosphoramide |
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| Gene, Accession, CAS # | CAS: 52-24-4 |
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| Catalog # | 23745-250 |
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| Order / More Info | Thio-TEPA from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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