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| Product Name | 15-deoxy-Δ12,14-Prostaglandin J2-biotin |
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| Description | 15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2; Item No. 18570) is one of the cyclopentenone PGs, which have documented metabolic (peroxisome proliferator-activated receptor γ-activating), antimitotic, and antiproliferative effects.{410,1349,13037} The activity of the compounds in this class, which includes PGs in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical (i.e., non-G protein-coupled receptor) pathways. 15-deoxy-.DELTA.12,14-PGJ2-biotin is an affinity probe which allows 15-deoxy-.DELTA.12,14-PGJ2 to be detected through an interaction with the biotin ligand. 15-deoxy-.DELTA.12,14-PGJ2-biotin was designed to allow 15-deoxy-.DELTA.12,14-PGJ2 to be detected in complexes with nuclear receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of the cyclopentenone PGs. |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 15-deoxy-Δ12,14-PGJ2-biotin |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 10141-500 |
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| Order / More Info | 15-deoxy-Δ12,14-Prostaglandin J2-biotin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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