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| Antigenic Specificity | Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.Subcellular location: Cell membrane, Multi-pass membrane protein. Cell junction ?? synapse ?? postsynaptic cell membrane, Multi-pass membrane protein.Tissue specificity: Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. Also known as: ACH10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10, NACHRA10. |
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| Immunogen | A synthetic peptide from c-terminal region of human CHRNA10 (Neuronal acetylcholine receptor subunit alpha-10) conjugated to an immunogenic carrier protein was used as the antigen. |
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| Other Names | si:dkey-24p1.3|ALPHA 10 nAChR |
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| Gene, Accession # | Gene ID: 57053 |
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| Catalog # | ABIN571796 |
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| Price | |
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| Order / More Info | Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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