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| Product Name | Recombinant Human Nuclear inhibitor of protein phosphatase 1 (PPP1R8) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 52.1kDa. Full Length of Isoform 2: 1-209aa. N-terminal GST-tagged. Homo sapiens (Human). Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Protein phosphatase 1 regulatory inhibitor subunit 8 |
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| Gene, Accession, CAS # | PPP1R8, UniProt: Q12972 |
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| Catalog # | RPC22999 |
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| Order / More Info | Recombinant Human Nuclear inhibitor of protein phosphatase 1 (PPP1R8) from BIOMATIK |
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| Product Specific References | n/a |
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