| 产品详情 |
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| Product Name | AT7867 |
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| Description | AT7867 is a potent inhibitor of Akt isoforms Akt1, 2, and 3 (IC50s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC50s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety of cancer cell lines in vitro and suppresses tumor growth of PTEN-deficient xenografts in mice. MW: 337.9. Purity ≥97% by HPLC |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine |
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| Gene, Accession, CAS # | CAS: 857531-00-1 |
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| Catalog # | B2178-1 |
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| Order / More Info | AT7867 from BIOVISION, INC. |
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| Product Specific References | n/a |
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