| 产品详情 |
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| Antigenic Specificity | MYOC |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MYOC Antibody is a Rabbit Polyclonal antibody against MYOC. Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina (PMID: 9176893; 9169133). It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) (PMID: 21709622). MYOC has a molecular weight of 55-57 kDa, besides, a 66-kDa form, which could be a result of post-translational modifications, has also been reported in some researches (PMID: 9497363; 12150989). |
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| Immunogen | Recombinant protein of human MYOC. |
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| Other Names | GPOA; JOAG; TIGR; GLC1A; JOAG1; myocilin; trabecular meshwork inducible glucocorticoid response; MYOC |
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| Gene, Accession # | MYOC, Gene ID: 4653, SwissProt: Q99972 |
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| Catalog # | abx001338 |
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| Price | |
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| Order / More Info | MYOC Antibody from ABBEXA |
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| Product Specific References | n/a |
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