| 产品详情 |
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| Antigenic Specificity | DCC |
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| Clone | AXEL1 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, λ |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | FC, FuncS |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-DCC Recombinant Antibody (AXEL1). Provided herein is a Mouse monoclonal antibody, which binds to DCC Netrin 1 Receptor (DCC). The antibody can be used for immunoassay techniques, such as FC, FuncS. DCC is a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated |
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| Immunogen | Recombinant human DCC fibronectin domain 5 |
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| Other Names | DCC Netrin 1 Receptor; Immunoglobulin Superfamily DCC Subclass Member 1; Deleted In Colorectal Carcinoma; Colorectal Cancer Suppressor; Tumor Suppressor Protein DCC; IGDCC1; Immunoglobulin Superfamily, DCC Subclass, Member 1; Putative Colorectal Tumor Suppressor; |
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| Gene, Accession # | Gene ID: 1630, UniProt: P43146 |
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| Catalog # | CBMAB-D0332-YC |
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| Price | |
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| Order / More Info | DCC Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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