| 产品详情 |
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| Antigenic Specificity | KPNA2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KPNA2 Antibody is a Rabbit Polyclonal antibody against KPNA2. The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq, Jul 2008]. |
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| Immunogen | Recombinant protein of human KPNA2. |
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| Other Names | Importin subunit alpha-1; Karyopherin subunit alpha-2; RAG cohort protein 1; SRP1-alpha; KPNA2; RCH1; SRP1; karyopherin alpha 2 (RAG cohort 1; importin alpha 1); IPOA1; QIP2; SRP1alpha; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); RAG cohort 1; importin alpha 1; importin alpha 2; importin subunit alpha-2; importin-alpha-P1; pendul |
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| Gene, Accession # | KPNA2, Gene ID: 3838, SwissProt: P52292 |
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| Catalog # | abx001367 |
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| Price | |
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| Order / More Info | KPNA2 Antibody from ABBEXA |
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| Product Specific References | n/a |
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