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Product Name | Interleukin 12 (IL12) (Active) protein |
Description | Interleukin 12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. The p40 subunit of IL-12 has been shown to have extensive amino acid sequence homology to the extracellular domain of the human IL-6 receptor while the p35 subunit shows distant but significant sequence similarity to IL-6, G-CSF, and chicken MGF. These observations have led to the suggestion that IL-12 might have evolved from a cytokine/soluble receptor complex. Human and mouse IL-12 share 70% and 60% amino acid sequence homology in their p40 and p35 subunits, respectively. IL-12 apparently shows species specificity with human IL-12 reportedly showing minimal activity in the mouse system. Synonym: Interleukin-12 ( IL-12), Human 0. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | IL-12 p40|il12b|il12p40.b|zgc:152789|LOC100217488|IL-12B|IL12B|IL-12p35|Il-12a|Ll12a|p35|Il12|CLMF|CLMF2|NKSF|NKSF2|IL-12p40 |
Gene, Accession, CAS # | Gene ID: 16159, 493741, 84405 |
Catalog # | ABIN988033 |
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Order / More Info | Interleukin 12 (IL12) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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