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Product Name | Calpain Inhibitor I, ALLN |
Description | A cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 0.5 nM). Inhibits neutral cysteine proteases and the proteasome (Ki = 6 µM). Can initiate apoptosis in HL-60 cells but blocks dexamethasone-induced apoptosis in thymocytes and cycloheximide-induced apoptosis in metamyelocytes. Inhibits cyclin B degradation and arrests the cell cycle at G1/S and at meta-/anaphase. MW: 383.54. Purity ≥95% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Ac-LLnL-CHO, MG-101, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal, N-Acetyl-Leu-Leu-Nle-al |
Gene, Accession, CAS # | CAS: 110044-82-1 |
Catalog # | 1834-5 |
Price | |
Order / More Info | Calpain Inhibitor I, ALLN from BIOVISION, INC. |
Product Specific References | n/a |
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