| 产品详情 |
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| Antigenic Specificity | CD200 |
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| Clone | OX-2 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1, κ |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE anti-rat CD200. CD200, known as OX-2, is a type I membrane glycoprotein member of the Ig supergene family. CD200 is expressed on B cells, a subset of T cells, thymocytes, follicular dendritic cells, neurons, keratinocytes, vascular endothelium, and some smooth muscle. The interaction of CD200 with CD200 receptor provide a potent costimulatory T-cell signal in the presence of TCR signaling, stimulate macrophages, and inhibit mast cell degranulation. It was reported that increased expression of OX-2 on DC was associated with inhibition of cytokine production and renal allograft rejection. Incubation of lymphocytes with OX-2 Fc inhibits a primary mixed lymphocyte reaction in vitro, decreased IL-2 and IFN-γ production, increased IL-4 and IL-10 production. In vivo infusion of OX-2 Fc promotes both skin and renal graft survival and decreases the antibody response. The OX-2 antibody reacts with rat OX-2 antigen. |
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| Immunogen | n/a |
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| Other Names | OX-2 antigen, MRC |
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| Gene, Accession # | Gene ID: 24560 |
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| Catalog # | 204807 |
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| Price | |
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| Order / More Info | CD200 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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