| 产品详情 |
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| Antigenic Specificity | CD204 |
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| Clone | 7G5C33 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse CD204. CD204, also known as scavenger receptor A (SR-A) and the macrophage scavenger receptor (MSR), is one of the phagocytic pattern-recognition receptors (PRRs) expressed on macrophages and dendritic cells. CD204 was initially identified as a receptor mediating recognition and internalization of low-density lipoprotein (LDL) by macrophages and playing critical roles in atherogenesis. Recent studies have revealed that CD204 recognizes apoptotic cells, modified lipid proteins, and exogenous pathogen-associated molecular patterns (PAMPs), which results in the induction of innate immune and inflammatory responses. CD204 can act as a co-receptor for Toll-like receptors, such as TLR3, TLR4, or TLR9, to facilitate the expression of proinflammatory cytokines. CD204 has been implicated in several pathological processes such as Alzheimer’s disease, sepsis, ischemic injury, and coronary artery disease. |
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| Immunogen | Partial mouse CD204 recombinant protein (79-458 a.a.) expressed in 293E cells. |
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| Other Names | Macrophage scavenger receptor 1 (Msr1), Scavenger receptor type A (SR-A), SRA |
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| Gene, Accession # | Gene ID: 20288 |
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| Catalog # | 676202 |
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| Price | |
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| Order / More Info | CD204 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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