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Product Name | LY-404,039 |
Description | Purity ~98% (NMR). A highly selective and potent agonist for recombinant human mGlu2 and mGlu3 receptors (Ki = 149nM and 92nM, respectively) and for rat neurons mGlu2/3 receptors (Ki = 88nM). Negligible interactions with other mGlu receptors and ionotropic glutamate receptors, glutamate transporter subtypes, monoamine and other receptors. Widely used for investigating neuropsychiatric disorders in animal models and developing potential treatment for human mental disorders, such as schizophrenia. Formula: C7H9NO6S Solubility: DMSO or dilute NaOH Primary Target: mGlu2 & mGlu3 Primary Target Ki: 149nM and 92nM for human mGlu2 and mGlu3, respectively. |
Size | 5mg |
Concentration | n/a |
Applications | n/a |
Other Names | LY-404,039 ((1R,4S,5S,6S)-4-[[(2S)-2-Amino-4-(methylthio)-1-oxobutyl]amino]-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid 2,2-dioxide) |
Gene, Accession, CAS # | n/a |
Catalog # | 217527 |
Price | |
Order / More Info | LY-404,039 from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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