| 产品详情 |
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| Antigenic Specificity | EGFRv3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EGFRv3 Polyclonal Antibody. • Target Background: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn a |
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| Immunogen | KLH conjugated synthetic peptide derived from human EGFRvIII. Immunogen Range: 1-50/1081 |
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| Other Names | ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR |
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| Gene, Accession # | Gene ID: 1956, SwissProt: P00533 |
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| Catalog # | bs-2558R |
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| Price | |
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| Order / More Info | EGFRv3 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Wang, J. et al. (2011) PJMS 27.3, 1576-1587. PubMed: N/A // Wehrenberg-Klee, Eric, et al. Am J Nucl Med Mol Imaging 2015;5(4):379-389. PubMed: 26269775 // Wei, Jian-wei, et al. (2016) Cancer Lett. PubMed: 27317648 // Agnes, Richard S., et al. (2012)Mol Cancer Ther. 11.10:2202-2211. PubMed: 22807580 // Kang, Chun-Sheng, et al.(2016) Cancer Lett. PubMed: 27725228 // Liu et al. (2016) Oncotarge. 7:4680-94. PubMed: 26717039 // Khelwatty et al. (2017) Oncotarget. 8:7666-7677. PubMed: 28032593 |
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