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| Product Name | CRT Inhibitor, iCRT5 |
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| Description | Cell-permeable. A potent inhibitor of the β-catenin-responsive transcription (CRT) in the nucleus. iCRT5 inhibits Wnt responsive STF16 luciferase (STF16-Luc) with an IC50 of 18 nM. It acts by disrupting the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin. However, it displays minimal or less prominent effect on non-canonical Wnt signaling and other pathways such as Hh, JAK/STAT, and Notch signaling. MW: 367.44. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (Z)-4-(5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 1896-25 |
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| Order / More Info | CRT Inhibitor, iCRT5 from BIOVISION, INC. |
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| Product Specific References | n/a |
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