| 产品详情 |
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| Antigenic Specificity | CEACAM1/CEACAM5 |
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| Clone | 4/3/17 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1:200-1:400, Flow Cytometry: 1.2 µg/1x10^6 cells, Immunohistochemistry (Frozen): 1-2 µg/1x10^6 cells, Western Blot: 4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CEACAM1/CEACAM5 Monoclonal Antibody (4/3/17). Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. |
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| Immunogen | n/a |
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| Other Names | pan CEACAM, Carcinoembryonic antigen-related cell adhesion molecule 1, BGP, BGP-1, CD66a, Biliary glycoprotein 1, Carcinoembryonic antigen-related cell adhesion molecule 5, CEA, CD66e |
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| Gene, Accession # | Entrez: 1048, 634; Uniprot: P06731, P13688 |
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| Catalog # | MA1-17767 |
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| Price | |
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| Order / More Info | CEACAM1/CEACAM5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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