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Product Name | Human CellExp™ Recombinant Ebolavirus BDBV Small/secreted Glycoprotein (sGP) |
Description | EBOV encodes seven structural proteins: nucleoprotein (NP), polymerase cofactor (VP35), (VP40), GP, transcription activator(VP30), VP24, and RNA polymerase (L). GP protein contains 160-kDa envelope-attached glycoprotein (GP) and a 110 kDasecreted glycoprotein (sGP). GP is a class I fusion protein which assembles as trimers on viral surface and plays an importantrole in virus entry and attachment. Mature GP is a disulfide-linked heterodimer formed by two subunits, GP1 and GP2, whichare generated from the proteolytical process of GP precursor (pre-GP) by cellular furin during virus assembly. GP1 isresponsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry |
Size | 10 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Ebola sGP, Ebolavirus BDBV (subtype Bundibugyo,strain Uganda 2007) |
Gene, Accession, CAS # | GP, Gene ID: 9487265, Accession: B8XCN1 |
Catalog # | P1059-10 |
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Order / More Info | Human CellExp™ Recombinant Ebolavirus BDBV Small/secreted Glycoprotein (sGP) from BIOVISION, INC. |
Product Specific References | n/a |
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