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| Product Name | Human CellExp™ IL-6 Rα, Human Recombinant |
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| Description | IL-6 mediates its biological effects through the type I IL-6 receptor system that consists of two chains, IL-6Rα and gp130. The IL-6Rα chain is the binding component specific to IL-6; while the gp130 only transmits signals of IL-6 when bound to IL-6Rα. The gp130 also can transmit signals from LIF, OSM, CNTF, IL-11 and CT-1 in conjunction with other receptor subunits. The low-affinity binding site for IL-6 is composed of IL-6Rα alone. IL-6Rα is expressed in a wide range of cells including T cells, fibroblasts and macrophages. Soluble IL-6Rα which consists of only the extracellular domain of the IL-6Rα chain, acts as an agonist of IL-6 activity at low concentrations. Recombinant human sIL-6Rα is |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | soluble IL-6 receptor alpha, B cell stimulatory factor-2, CD126 |
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| Gene, Accession, CAS # | IL6RA, Gene ID: 3570, Accession: P08887 |
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| Catalog # | 7102-50 |
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| Price | |
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| Order / More Info | Human CellExp™ IL-6 Rα, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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