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Product Name | Human CellExp™ IL-1 RII /CD121b, human recombinant |
Description | Interleukin-1 receptor type 2 (IL1R2) also known as CD121 antigen-like family member B (CDw121b), IL-1 type II receptor, Interleukin-1 receptor type II, belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R2 is non-signaling receptor for IL1A, IL1B and IL1RN, reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | CD121b, IL1RB, IL1R2, CDw121b |
Gene, Accession, CAS # | IL1R2, Gene ID: 7850, Accession: P27930 |
Catalog # | 7392-50 |
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Order / More Info | Human CellExp™ IL-1 RII /CD121b, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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