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| Product Name | CD40 Ligand, Soluble, Recombinant, Human (TRAP, sCD40, CD40L, CD154) |
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| Description | Purity ~98% (RP-HPLC, SDS-PAGE). CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2. Source: Recombinant protein corresponding to 149aa of human sCD40, expressed in E. coli. Molecular Weight: ~16.31kD Biological Activity: The ED50, as determined by the dose-dependant stimulation of IL-12 and IL-8 induction by PMB (Peripheral Mononuclear) cells, was found to be 5-10ng/ml. AA Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gln-Lys-Gly-Asp. Protein Content: Protein quantitation was carried out by two independent methods |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299338 |
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| Order / More Info | CD40 Ligand, Soluble, Recombinant, Human (TRAP, sCD40, CD40L, CD154) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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