| 产品详情 |
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| Product Name | EPZ-5676 |
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| Description | A potent and selective inhibitor of DOT1L methyltransferase (Ki = 80 pM). EPZ-5676 displays 37,000-fold selectivity over all other tested methyltransferases. It inhibits H3K79 methylation and MLL-fusion target gene expression and displays potent cell killing selective for acute leukemia lines bearing MLL translocations. MW: 562.71. Purity ≥98% by HPLC |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol |
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| Gene, Accession, CAS # | CAS: 1380288-87-8 |
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| Catalog # | 2382-1 |
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| Price | |
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| Order / More Info | EPZ-5676 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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