| 产品详情 |
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| Product Name | Recombinant Human E3 SUMO-protein ligase RanBP2 (RANBP2), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 24.8kDa. Partial: 2601-2802aa. N-terminal 6xHis-tagged. Homo sapiens (Human). E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell cycle |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 358KDA nucleoporin; Nuclear pore complex protein Nup358; Nucleoporin Nup358; Ran-binding protein 2 |
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| Gene, Accession, CAS # | RANBP2, UniProt: P49792 |
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| Catalog # | RPC24913 |
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| Order / More Info | Recombinant Human E3 SUMO-protein ligase RanBP2 (RANBP2), partial from BIOMATIK |
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| Product Specific References | n/a |
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