| 产品详情 |
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| Antigenic Specificity | Caspase 1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 1 Polyclonal Antibody. Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis (1). The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a tetramer to form the active enzyme. Caspase-1/ICE (IL-1b converting enzyme) is similar to the cell death gene CED-3 of Caenorhabditilis elegans and regulates multiple proinflammatory cytokines, including interleuk |
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| Immunogen | n/a |
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| Other Names | ICE, IL1BC, P45 |
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| Gene, Accession # | Entrez: 12362, 834; Uniprot: P29452, P29466 |
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| Catalog # | PA1-41214 |
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| Price | |
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| Order / More Info | Caspase 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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