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| Antigenic Specificity | Caspase-3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat, bovine, goat |
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| Isotype | n/a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P), IF(ICC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 3 Polyclonal Antibody, FITC Conjugated. • Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons |
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| Immunogen | KLH conjugated synthetic peptide derived from human Caspase 3(Active). Immunogen Range: 60-100/277 |
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| Other Names | CPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3 |
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| Gene, Accession # | Gene ID: 836, SwissProt: P42574 |
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| Catalog # | bs-0081R-FITC |
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| Price | |
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| Order / More Info | Caspase-3 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Jiang, J. et al. (2011) World J Gastroenterol.17(31):3605-13. PubMed: 21987607 // Lin, Chia-Fa, et al. (2016) Molecules21.3: 334. PubMed: 26978332 |
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