产品详情 |
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Antigenic Specificity | CBX4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CBX4 Polyclonal Antibody. • Target Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via |
Immunogen | KLH conjugated synthetic peptide derived from human CBX4. Immunogen Range: 415-445/560 |
Other Names | PC2; NBP16; E3 SUMO-protein ligase CBX4; Chromobox protein homolog 4; Polycomb 2 homolog; hPc2; CBX4 |
Gene, Accession # | Gene ID: 8535, SwissProt: O00257 |
Catalog # | bs-17376R |
Price | |
Order / More Info | CBX4 Antibody from BIOSS ANTIBODIES |
Product Specific References | Han, Xiao, et al. (2015) Graefes Arch Clin Exp Ophthalmol. PubMed: 25877955 |
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