| 产品详情 |
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| Product Name | Tyrosyl-DNA Phosphodiesterase 1 (TDP1) peptide |
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| Description | Tdp1 is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. It hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. It acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. It has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. It has no exonuclease activity towards DNA or RNA with a 3'phosphate. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | tdp1|MGC83708|TDP1|F8M21.60|F8M21_60|tyrosyl-DNA phosphodiesterase 1|2810481F14Rik|4921509N21Rik|AI838772|AW493413|E430034L06Rik|MLZ-501|SCAN1 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN938152 |
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| Price | |
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| Order / More Info | Tyrosyl-DNA Phosphodiesterase 1 (TDP1) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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