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| Product Name | G 5555 |
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| Description | High affinity group 1 PAK (pan-PAK1, 2 and 3) inhibitor (Ki = 3.7 nM; pMEK IC50 = 69 nM). Of 235 kinases tested, other than PAK1, eight (PAK2, PAK3, KHS1, Lck, MST3, MST4, SIK2, and YSK1) were inhibited >70%. Exhibits low hERG channel activity (<50% inhibition at 10 μM). Orally bioavailable. Purity 98%. MW (observed): 492.96 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one |
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| Gene, Accession, CAS # | CAS: 1648863-90-4 |
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| Catalog # | 6051/50 |
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| Price | |
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| Order / More Info | G 5555 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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