| 产品详情 |
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| Product Name | GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) protein (His tag) |
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| Description | Golgi-associated ATPase Enhancer of 16 kDa (GATE-16), also known as Apg8p2 and GABARAPL2, is a 117 amino acid (aa) polypeptide and a member of the autophagy-related 8 (Atg8) family of proteins. GATE-16 has 100% aa sequence identity with its mouse and rat orthologs, and is orthologous to the yeast Atg8. Atg8 family members show structural similarity with ubiquitin, but lack aa sequence similarity. GATE-16 is best known for its role in autophagy. GATE-16 covalently attaches to phosphatidylethanolamine (PE) the phagophore (autophagosome precursor) membrane using a ubiquitin-like conjugation system that includes ubiquitin-activating (E1)-, ubiquitin-conjugating (E2)-, and ubiquitin ligase (E3)-like enzymes. Here it is involved in the later stages of autophagosome formation. It may also be involved in cargo recruitment to autophagosomes. |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | GABARAPL2|atg8|gef2|gate16|gate-16|Gef2|ATG8|ATG8C|GATE-16|GATE16|GEF-2|GEF2|zgc:92319|0610012F20Rik|2900019O08Rik|AI173605 |
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| Gene, Accession, CAS # | Gene ID: 11345 |
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| Catalog # | ABIN2745693 |
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| Order / More Info | GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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