产品详情 |
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Product Name | PG-01037 (hydrochloride) |
Description | A selective dopamine D3 receptor antagonist (Kis = 0.7, 93, and 375 nM for HEK293 cells expressing human D3, D2, and D4 receptors, respectively); inhibits quinpirole-induced stimulation of mitogenesis in CHO cells expressing human dopamine D3 receptors (EC50 = 3 nM); reduces progressive-ratio methamphetamine self-administration in rats allowed extended access at 32 mg/kg; reduces loss of dopaminergic neurons in the substantia nigra pars compacta and improves motor performance in the coat-hanger test in a mouse model of MPTP-induced Parkinson's disease |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 790658-27-4 PG01037 D-3 2 4 HEK-293 Chinese hamster ovary 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
Gene, Accession, CAS # | CAS: 675599-62-9 |
Catalog # | 22079-1 |
Price | |
Order / More Info | PG-01037 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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