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| Product Name | Natural Resistance Associated Macrophage Protein, Rat (Nramp2) (Control Peptide) |
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| Description | Highly purified. A 19aa Peptide sequence located at the predicted cytoplasmic loop # 4 of rat NRAMP2. Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associated Macrophage Protein (Nramp1). Recently a second member of NRAMP family, termed NRAMP2/DMT/DCT1 (Divalent Metal ion Transporter 1 or Divalent Cation Transporter 1), has been identified (human, rat and mouse 568 aa, ~65% identity with NRAMP1). Unlike NRAMP1, NRAMP2 expression is more ubiquitous and has been detected in most tissues. It is dramatically up-regulated by iron starvation in the intestine. NRAMP2 gene produces two alternatively spliced transcripts generated by alternative use of two 3' exons encoding distinct C-termini of the protein as well as distinct 3' untranslated regions (UTRs). Interestingly, one Nramp2 mRNA contains an iron-resp |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N0020-01 |
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| Price | |
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| Order / More Info | Natural Resistance Associated Macrophage Protein, Rat (Nramp2) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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