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Product Name | Neurotrophin 4 (NTF4) (AA 81-210) (Active) protein |
Description | Neurotrophin-4 (NT-4), also known as NT-5, is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-3. Human NT-4 shares 48 - 52% aa sequence identity with human beta-NGF, BDNF, and NT-3.Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds. NT-4 is expressed highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. NT-4 binds and induces receptor dimerization and activation of TrkB. NT-4 can signal through TrkB receptors and promotes the survival of peripheral sensory sympathetic neurons.Recombinant human Neurotrophin-4 (rhNT-4) produced in E.coli is a noncovalently linked homodimer containing two non-glycosylated polypeptide chains of 131 amino acids. A fully biologically active molecule, rhNT-4 has a molecular mass of 28.1kDa analyzed by reducing SDS-PAGE. Synonyms: Neurotrophin-4, Neurotrophic 4/5 (NT-4/NT-5) |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | NTF5|GLC10|GLC1O|NT-4|NT-4/5|NT-5|NT4|NT5|NT4P|Ntf5|2900040K06Rik|AI462899|NT4/5|Ntf-5|Ntf4 |
Gene, Accession, CAS # | Gene ID: 4909 |
Catalog # | ABIN2018284 |
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Order / More Info | Neurotrophin 4 (NTF4) (AA 81-210) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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