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| Product Name | Neurotrophin 4 (NTF4) (AA 80-209) (Active) protein |
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| Description | Neurotrophin-4 (NT-4) is a small secreted cytokine, and belongs to the Neurotrophin (NT) family, which also includes Brain Derived Neurotropic Factor (BDNF), Nerve Growth Factor (NGF), and NT-3. NT family members are all derived from similar sized protein precursors, composed of N-terminal propeptides and C-terminal mature domains, which are separated by posttranslational proteolytic cleavage. NT-4 (along with NT-3) is foundin the brains of mammals . In vivo, NT-4 binds to the common receptor, p75NTR, and a tyrosine kinase receptor, TrkB. The heterotrimeric complex activates the NF-kappaB transcription factor. NT-4 is essential for the differentiation and wiring regulation of the central and peripheral nervous systems during development, and is related to important diseases including Alzheimer's.Recombinant mouse Neurotrophin-4 (rmNT-4) produced in E. coli is a noncovalently linked homodimer containing two non-glycosylated polypeptide chainsof 131 amino acids. A fully biologically active molecule, rmNT-4 has a molecular mass of 14.0kDaanalyzed by reducing SDS-PAGE. Synonyms: Neurotrophin-4, Neurotrophic 4/5 (NT-4/NT-5) |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NTF5|GLC10|GLC1O|NT-4|NT-4/5|NT-5|NT4|NT5|NT4P|Ntf5|2900040K06Rik|AI462899|NT4/5|Ntf-5|Ntf4 |
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| Gene, Accession, CAS # | Gene ID: 78405 |
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| Catalog # | ABIN2018283 |
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| Order / More Info | Neurotrophin 4 (NTF4) (AA 80-209) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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