| 产品详情 |
| Edit |   |
| Antigenic Specificity | AICD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 50 µg |
| Concentration | n/a |
| Applications | ELISA, IHC, Western Blot (WB), Immunofluorescence Microscopy (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-AICD. APP intracellular domain (AICD) is a peptide fragment that results from intramembraneous proteolysis of the amyloid precursor protein (APP). APP is a single-pass transmembrane protein that is involved in the pathophysiology of Alzheimer's disease (AD). APP is cleaved by gamma-secretase that releases the AICD into the cytoplasm. Soon after its release from the membrane, AICD is rapidly degraded in the cytoplasm partly by insulin degrading enzymes. |
| Immunogen | n/a |
| Other Names | Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, SIG-39148-050 |
| Gene, Accession # | Gene ID: 351 |
| Catalog # | 811901 |
| Price | |
| Order / More Info | AICD Antibody from BIOLEGEND |
| Product Specific References | PubMed: 22031884 |
| 产品资料 |
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