| 产品详情 |
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| Antigenic Specificity | EFHA1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EFHA1 Polyclonal Antibody. Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927). |
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| Immunogen | n/a |
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| Other Names | 1110008L20Rik; EF hand domain family A1; EF hand domain family; member A1; EF-hand domain-containing family member A1; Smhs2 homolog |
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| Gene, Accession # | Entrez: 221154; Uniprot: Q8IYU8 |
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| Catalog # | PA5-71432 |
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| Price | |
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| Order / More Info | EFHA1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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