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Product Name | Recombinant Hepatitis B virus genotype C subtype adr Large envelope protein (S), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 20.9kDa. Partial: 2-181aa. N-terminal 6xHis-tagged. Hepatitis B virus genotype C subtype adr (isolate Japan/Nishioka/1983) (HBV-C). The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane (Probable). In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein (By similarity). |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | L glycoprotein; L-HBsAg; LHB; Large S protein; Large surface protein; Major surface antigen |
Gene, Accession, CAS # | S, UniProt: P31868 |
Catalog # | RPC25166 |
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Order / More Info | Recombinant Hepatitis B virus genotype C subtype adr Large envelope protein (S), partial from BIOMATIK |
Product Specific References | n/a |
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