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| Product Name | ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5) (AA 141-247) protein (TRX tag) |
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| Description | ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FLT1 (VEGFR1) receptor tyrosine kinase which was functionally required for efficient xenograft tumor formation, as demonstrated by shRNA knockdown experiments.Alternative Names: ATP-binding cassette sub-family B member 5, P-glycoprotein ABCB5, ABCB5 P-gp, ABCB5, |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MDR1|wu:fi81f06|mdr1|im:7158730|wu:fc18f02|ABCB5alpha|ABCB5beta|EST422562|9230106F14Rik|RGD1566342|ABCB5 |
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| Gene, Accession, CAS # | Gene ID: 340273 |
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| Catalog # | ABIN1692395 |
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| Order / More Info | ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5) (AA 141-247) protein (TRX tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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