| 产品详情 |
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| Antigenic Specificity | AFF1-Specific |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-AFF1-Specific polyclonal antibody. This gene encodes a member of the AF4/ lymphoid nuclear protein related to AF4/Fragile X E mental retardation syndrome family of proteins, which have been implicated in childhood lymphoblastic leukemia, Fragile X E site mental retardation, and ataxia. It is the prevalent mixed-lineage leukemia fusion gene associated with spontaneous acute lymphoblastic leukemia. Members of this family have three conserved domains: an N-terminal homology domain, an AF4/ lymphoid nuclear protein related to AF4/Fragile X E mental retardation syndrome domain, and a C-terminal homology domain. The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling |
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| Immunogen | AF4/FMR2 family, member 1 |
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| Other Names | AFF1, MLLT2, AF4 MLL, PBM1, AF 4 |
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| Gene, Accession # | Gene ID: 4299, UniProt: P51825 |
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| Catalog # | FNab00195 |
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| Price | |
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| Order / More Info | AFF1-Specific Antibody from FINETEST |
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| Product Specific References | n/a |
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